Carfilzomib MOA, Dosage, Cost, Side Effects, Survival Rate

 Carfilozomib FAQ

Kyprolis(r) (carfilzomib) Product Image


What is Carfilzomib?

It's a prescription drug used to treat patients with relapsed or refractory multiple myeloma.


Carfilzomib (MOA) Mechanism of Action

It works by either slowing or stopping the growth of cancer cells in your body.


Carfilzomib Dosage

One single dose in a vial is either 30 mg or 60 mg.


Cost / Price of Carfilzomib

According to one source, the drug by itself is estimated to cost about $10,000 for a 28-day cycle, without health insurance.


Carfilzomib Generic

It's the generic name for Kyprolis.


Carfilzomib Side Effects

Common side effects may include:

  • agitation
  • black, tarry stools
  • bleeding gums
  • bloating or swelling of the face, hands, arms, lower legs, or feet
  • blood in the stools or urine
  • blurred vision
  • burning, itching, crawling, prickling, numbing, or tingling sensations
  • chest tightness or pain
  • confusion
  • cough
  • reduced responsiveness or awareness
  • decreased urine output
  • depression
  • troubled or labored breathing
  • difficulty with movement
  • dizziness
  • drowsiness
  • rapid, slow, or irregular heartbeat
  • headache
  • hoarseness
  • hostility
  • irritability
  • loss of consciousness
  • lower back or side pain
  • twitching or muscle spasms
  • nausea
  • numbness or tingling in the hands, feet, or lips
  • difficult or painful urination
  • pale skin
  • pinpoint red spots on the skin
  • pounding in the ears
  • fast weight gain
  • seizures
  • severe sleepiness
  • tingling of the feet or hands
  • trembling
  • difficult breathing
  • white spots, sores, or ulcers in the mouth
  • awkwardness or unsteadiness
  • uncommon bruising or bleeding
  • uncommon dullness, fatigue, drowsiness, weakness, of feeling of sluggishness
  • uncommon weight loss or gain
  • vomiting

Carfilzomib Survival Rate

Patients taking this drug survived 18 months at 64.5%.


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