Xtandi FAQ: Is It Right For You?
What is Xtandi?
It's a prescription drug used to treat prostate cancer, which doesn't respond any longer to other treatments.
What's Xtandi (MOA) Mechanism of Action?
It prevents the translocation of the AR from the cytoplasm to the nucleus. Inside the nucleus, it inhibits AR binding to chromosomal DNA, which prevents additional transcription of tumor genes.
Xtandi Dosage
Recommended dose is 160 mg given orally only once a day.
Cost / Price of Xtandi
A supply of 120 capsules at 40 mg of Xtandi costs about $13,698, without health insurance.
Xtandi Generic
Its generic name is enzalutamide.
Xtandi Side Effects
Common side effects include:
- headache
- high blood pressure
- dizziness
- joint pain
- hot flashes
- reduced appetite
- weakness
- exhaustion
- constipation
- back pain
- diarrhea
- bloody urine
- muscle pain