Pertuzumab FAQ
What is Pertuzumab?
It's a drug used to treat breast cancer that has spread to other parts of the body.
Pertuzumab (MOA) Mechanism of Action
It works by inhibiting ligand-dependent HER2-HER3 dimerization and reducing signaling through intracellular pathways like phosphatidylinositol 3-kinase.
Pertuzumab Dosage
The first dose is 840 mg given as a 60-minute intravenous infusion, then every 3 weeks at a dose of 420 mg.
Cost / Price of Pertuzumab
A supply of 420 mg per 14 milliliters intravenous solution costs about $5,534, without health insurance.
Pertuzumab Generic
It's the generic name for Perjeta.
Pertuzumab Side Effects
Common side effects may include:
- black, tarry stools
- numbing, burning, tingling, or painful sensations
- chills
- cough
- rapid heartbeat
- fever
- hives, itching or rash
- hoarseness
- joint pain, stiffness, or swelling
- lower back or side pain
- difficult or painful urination
- pale skin
- redness of the skin
- sore throat
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- difficulty breathing or swallowing
- ulcers, sores, or white spots in the mouth
- awkwardness or unsteadiness
- uncommon bruising or bleeding
- uncommon fatigue or weakness
- weakness in the arms, hands, legs, or feet
Pertuzumab Survival Rate
Median overall survival was 43 months.
