Obinutuzumab MOA, Dosage, Cost, Side Effects, Survival Rate

 Obinutuzumab FAQ



What is Obinutuzumab?

It's a drug used to treat specific types of blood cancer like chronic lymphocytic leukemia.


Obinutuzumab (MOA) Mechanism of Action

It works by improving direct cell death and ADCC / ADCP effect, while decreasing CDC effect via glycoengineering.


Obinutuzumab Dosage

The initial dose was split up between day one at 100 mg and day two at 900 mg.


Cost / Price of Obinutuzumab

The cost for one six-month course of treatment is about $41,300, without health insurance.


Obinutuzumab Generic

It's the generic name for Gazyva, the trade drug name.


Obinutuzumab Side Effects

The most common side effects may include:

  • chills
  • flushing
  • fever
  • cough
  • chest tightness
  • bleeding gums
  • back pain
  • headache
  • black, tarry stools
  • blood in the stools or urine
  • hoarseness
  • lower back or side pain
  • nausea
  • pale skin
  • difficult or painful urination
  • pinpoint red spots on the skin
  • sore throat
  • difficulty breathing
  • troubled breathing with exertion
  • white spots, sores, or ulcers in the mouth
  • uncommon bruising or bleeding
  • uncommon weakness or fatigue
  • vomiting

Obinutuzumab Survival Rate

In a study, 75% of patients taking obinutuzumab survived to the end of the trial, resulting in 33% lower risk of death.


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