Obinutuzumab FAQ
What is Obinutuzumab?
It's a drug used to treat specific types of blood cancer like chronic lymphocytic leukemia.
Obinutuzumab (MOA) Mechanism of Action
It works by improving direct cell death and ADCC / ADCP effect, while decreasing CDC effect via glycoengineering.
Obinutuzumab Dosage
The initial dose was split up between day one at 100 mg and day two at 900 mg.
Cost / Price of Obinutuzumab
The cost for one six-month course of treatment is about $41,300, without health insurance.
Obinutuzumab Generic
It's the generic name for Gazyva, the trade drug name.
Obinutuzumab Side Effects
The most common side effects may include:
- chills
- flushing
- fever
- cough
- chest tightness
- bleeding gums
- back pain
- headache
- black, tarry stools
- blood in the stools or urine
- hoarseness
- lower back or side pain
- nausea
- pale skin
- difficult or painful urination
- pinpoint red spots on the skin
- sore throat
- difficulty breathing
- troubled breathing with exertion
- white spots, sores, or ulcers in the mouth
- uncommon bruising or bleeding
- uncommon weakness or fatigue
- vomiting
Obinutuzumab Survival Rate
In a study, 75% of patients taking obinutuzumab survived to the end of the trial, resulting in 33% lower risk of death.