Ramucirumab FAQ
What is Ramucirumab?
It's a drug used to treat stomach, colorectal, or non-small cell lung cancer.
Ramucirumab (MOA) Mechanism of Action
It's an antineoplastic agent and direct VEGFR2 antagonist which blocks the binding of natural VEGF.
Ramucirumab Dosage
Days 1 and 15: take ramucirumab at 8 mg/kg IV; days 1,8, and 15: take paclitaxel at 80 mg/m. Repeat cycle every 28 days. Continue till cancer improves or proves unacceptable.
Cost / Price of Ramucirumab
A supply of 10 milliliters of ramucirumab intravenous solution costs about $1,372.
Ramucirumab Generic
It's the generic name for Cyramza.
Ramucirumab Side Effects
Common side effects may include:
- spasms or back pain
- blurred vision
- numbing, crawling, itching, burning, prickling, or tingling sensations
- chest pain
- chills
- cloudy urine
- confusion
- cough
- coughing up blood
- reduced urine output
- dizziness, faintness, or lightheadedness when rising suddenly from sitting or lying position
- fainting
- rapid, slow, pounding, or irregular pulse or heartbeat
- feeling uncommonly cold
- fever
- headache
- increased thirst
- side or lower back pain
- cramps or muscle pain
- nausea
- nervousness
- nosebleeds
- difficult or painful urination
- pounding in the ears
- redness of the face, arms, neck, sometimes, upper chest
- seizures
- shivering
- shakiness in the legs, arms, hands, or feet
- sweating
- swelling of the face, hands, ankles, feet, or lower legs
- trembling or shaking of the feet or hands
- difficulty breathing
- uncommon fatigue or weakness
- vomiting
Ramucirumab Survival Rate
The results of a trial demonstrated an advantage with the addition of ramucirumab. The median overall survival was 9.6 months for patients receiving ramucirumab/paclitaxel combination.
