Kyprolis FAQ
What is Kyprolis?
It's a prescription drug used to treat adult patients with either refractory or relapsed multiple myeloma.
Kyprolis (MOA) Mechanism of Action
It works by acting as a selective proteasome inhibitor.
Kyprolis Dosage
The recommended beginning dose is 20 mg/m2 in cycle 1 on days 1 and 2. If tolerated, increase the dose to 27mg/m2 on day 8 of cycle 1.
Cost / Price of Kyprolis
A 28-day cycle costs about $10,000.
Kyprolis Generic
Carfilzomib is its generic drug name.
Kyprolis Side Effects
Common side effects may include:
- tiredness
- low blood cell count
- low blood platelet levels
- breathlessness
- diarrhea
- constipation
- nausea
- fever
- swelling of the extremities
- weakness
- upper respiratory tract infection
- runny or stuffy nose
- bronchitis
- pneumonia
- low blood potassium
- low blood calcium
- high blood sugar
- muscle spasms
- tingling and numbness in the extremities
- insomnia
- cough
- rash
- high blood pressure
Kyprolis Survival Rate
A study demonstrated that patients taking Kyprolis had a median overall survival of 47.8 months, versus 38.8 months in the Velcade group.
