Imbruvica MOA, Dosage, Cost, Side Effects, Survival Rate

 Imbruvica FAQ


What is Imbruvica?

It's medication used to treat specific types of blood cancer like small lymphocytic leukemia and chronic lymphocytic leukemia.


Imbruvica (MOA) Mechanism of Action

The drug develops a covalent bond with a cysteine residue in the BTK active site, which leads to inhibition of BTK enzymatic activity.


Imbruvica Dosage

Recommended dose is 420 mg once daily. Your doctor might adjust your particular dose as needed.


Cost / Price of Imbruvica

A supply of 90 140-mg capsules costs about $16,883, without health insurance.


Imbruvica Generic

There exists no generic version for this drug.


Imbruvica Side Effects

The common side effects may include:

  • bone and muscle pain
  • rash
  • bruising
  • feeling exhausted
  • ulcers or blisters in your mouth
  • fever
  • cough
  • difficulty breathing
  • diarrhea
  • nausea

Imbruvica Survival Rate

At 5 years, patients receiving ibrutinib treatment saw 70% overall survival rate.



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