Sorafenib Overview
What is Sorafenib?
Sorafenib is a medication used to treat thyroid, liver, and kidney cancer.
Sorafenib (MOA) Mechanism of Action
The drug works by either slowing or stopping the growth of cancer cells.
Sorafenib Dosage
The recommended dose is 400 mg taken twice daily without food at least one hour before or 2 hours after food.
Cost / Price of Sorafenib
The cost of sorafenib is about $23,379 for a supply of 120 200-mg tablets.
Sorafenib Generic
Sorafenib is the generic name for Nexavar.
Sorafenib Side Effects
Common side effects include:
- Bleeding gums
- Blistering, redness, peeling, or swelling of the palms of the hands or soles of the feet
- Bloating of the stomach or abdomen
- Blood in stools or urine
- Coughing up blood
- Difficulty with swallowing or breathing
- Increased vaginal bleeding or menstrual flow
- Tiredness
- Weakness
- Skin redness
- Hair loss
- Itching
- Peeling or dry skin
- Loss of appetite
- Constipation
Sorafenib Survival Rate
Survival rates at one year were 44% in the sorafenib group and only 33% in the placebo group.
