Regorafenib MOA, Dosage, Cost, Side Effects, Survival Rate

 Regorafenib FAQ

Stivargo 40 Mg Stivarga Tablet


What is Regorafenib?

It's a drug used to treat colon, rectum, colorectal, and liver cancer.


Regorafenib (MOA) Mechanism of Action

It works by blocking certain proteins, which in turn might prevent cancerous cells from multiplying.


Regorafenib Dosage

The recommended dose is 160 mg, or 40-mg tablets, taken orally once daily for the initial 21 days per 28-day cycle.


Cost / Price of Regorafenib

A supply of 84 40-mg costs about $20,718, without health insurance.


Regorafenib Generic

It's the generic name for Stivarga.


Regorafenib Side Effects

Common side effects may include:

  • anemia
  • increased liver enzymes
  • fatigue
  • protein in the urine
  • low calcium
  • low phosphorus
  • low white blood cells
  • reduced appetite
  • headache
  • confusion
  • vision changes
  • seizure
  • pain, bleeding, blisters, or severe rash in the palms of hands or the soles of feet
  • chest pain
  • breathlessness
  • faint headedness

Regorafenib Survival Rate

In a study, regorafenib proved to be superior to placebo in controlling the cancer: 41% versus 15% for placebo patients. 



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