Ruxolitinib FAQ
What is Ruxolitinib?
It's in a class of drugs known as kinase inhibitors.
Ruxolitinib (MOA) Mechanism of Action
It works by treating myelofibrosis and PV via blocking the signals which cause cancerous cells to grow. This helps to halt the spread of cancerous cells.
Ruxolitinib Dosage
The recommended beginning dose is 5 mg administered orally twice daily. Then, increasing the dose to 10 mg twice daily after a minimum of 3 days of treatment.
Cost / Price of Ruxolitinib
The current cost for 60 5-mg tablets is about $16,412, without health insurance.
Ruxolitinib Generic
Ruxolitinib is the generic name for Jakafi, the drug trade name.
Ruxolitinib Side Effects
Common side effects of ruxolitinib include:
- dizziness
- headache
- fatigue
- breathlessness
- weight gain
- gas
- diarrhea
- constipation
- bruising
- urinary tract infections
- bloating
- low blood platelet levels
Ruxolitinib Survival Rate
In a study, the patients receiving ruxolitinib saw a 31% longer overall survival rate.