Ruxolitinib MOA, Dosage, Cost, Side Effects, Survival Rate

 Ruxolitinib FAQ












What is Ruxolitinib?


It's in a class of drugs known as kinase inhibitors. 


Ruxolitinib (MOA) Mechanism of Action

It works by treating myelofibrosis and PV via blocking the signals which cause cancerous cells to grow. This helps to halt the spread of cancerous cells.


Ruxolitinib Dosage

The recommended beginning dose is 5 mg administered orally twice daily. Then, increasing the dose to 10 mg twice daily after a minimum of 3 days of treatment.


Cost / Price of Ruxolitinib

The current cost for 60 5-mg tablets is about $16,412, without health insurance.


Ruxolitinib Generic

Ruxolitinib is the generic name for Jakafi, the drug trade name.


Ruxolitinib Side Effects

Common side effects of ruxolitinib include:

  • dizziness
  • headache
  • fatigue
  • breathlessness
  • weight gain
  • gas
  • diarrhea
  • constipation
  • bruising
  • urinary tract infections
  • bloating
  • low blood platelet levels

Ruxolitinib Survival Rate

In a study, the patients receiving ruxolitinib saw a 31% longer overall survival rate.


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